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Drug Discovery_

HARNESSING NATURALLY GENERATED HUMAN-DERIVED

SMALL MOLECULES FOR BETTER THERAPEUTICS

We enable better drug discovery by probing the vastness of chemical space hidden within the human natural products, leveraging our platform technologies that leverage immense AI-powered computational genetics and chemistry engines to illuminate new frontiers for new medicines.

Our Approach

The Future
is inside us

Unlike synthetic compounds, human-derived natural products have been fine-tuned by evolution over millions of years. They’re inherently biocompatible, stable in human systems, and often have precise, functional roles in health and disease.
This evolutionary optimization gives BluMaiden a tremendous head start when it comes to discovering compounds that are both effective and safe. And it's this hidden reservoir of bioactive chemistry that BluMaiden is tapping into—guided by cutting-edge AI—to fuel our pipeline of small molecule therapeutics.

Illuminating Human-derived Chemical Dark Matter with QuantumBridgeAI™

With all the accumulated knowledge on natural bioactive compounds whose production is encoded in DNA, the vast majority of the human-derived natural product universe remain poorly annotated. This represents an immense untapped reservoir of DNA-level information on biosynthesis of yet unknown biological small molecules.

BluMaiden Biosciences has developed QuantumBridgeAI™, an AI model that translates the language of genomes into the language of small molecules. This revolutionary tool exponentially expands opportunities for discovering new bioactive natural products, bypassing the limitations of existing knowledge to interpret the Human-derived natural product dark matter.

Superior, Rapid, Cost-effective Candidate Nomination

MAIDEN™ Drug Discovery Platform

Our MAIDEN™ platform enhances the discovering new therapeutics and enables the probing of new and traditionally undruggable targets. By integrating our QuantumBridgeAI™ technology with human clinical evidence, MAIDEN™ therefore improves disease biology mechanism understanding and expands the frontiers of therapeutic discovery.

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FIND

BIND

VALIDATE

We bi-directionally identify genome encoded natural chemicals from human derived samples.

We match natural compounds to disease targets through computational chemistry approaches.

Virtual small molecule leads coupled to clinical evidence are validated against human targets.

Remarkable Therapeutics_

GENOMES

To

CHEMICAL SPACE

To

NEW THERAPEUTICS

Human Validation Upfront

Human evidence-guided small molecule discovery ensures bio-relevance from the outset. Extensive datasets yield patient population responses. Notably, traceability of the data back to clinical source throughout our process underscores its value.

Biocompatibility

The small molecules drug candidates, derived from humans, off inherent validation of their efficacy and the potential for favorable safety profiles from the outset.

Broad Therapeutic Potential

The microbiome plays a crucial role in numerous health and disease conditions, presenting ample opportunities to identify drugs for a wide range of ailments.

Drugging the Undruggable with a High Success Rate

Our approach significantly enhances the likelihood of discovering new therapeutics and successfully targeting traditionally challenging or “undruggable” molecular targets.

Human Validation Upfront

Human evidence-guided small molecule discovery ensures bio-relevance from the outset. Extensive datasets yield patient population responses. Notably, traceability of the data back to clinical source throughout our process underscores its value.

Biocompatibility

The small molecules drug candidates, derived from humans, off inherent validation of their efficacy and the potential for favorable safety profiles from the outset.

Broad Therapeutic Potential

The microbiome plays a crucial role in numerous health and disease conditions, presenting ample opportunities to identify drugs for a wide range of ailments.

Drugging the Undruggable with a High Success Rate

Our approach significantly enhances the likelihood of discovering new therapeutics and successfully targeting traditionally challenging or “undruggable” molecular targets.

Get in Touch

If you have a general question for us or want to explore a partnership opportunity, then please reach out to us here…

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